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770-71-8 - 1-Adamantanemethanol, 98% - 1-(Hydroxymethyl)adamantane - B23831 - Alfa Aesar

B23831 1-Adamantanemethanol, 98%

Codice CAS
770-71-8
Sinonimi
1-(Hydroxymethyl)adamantane

Dimensioni Prezzo ($) Quantità Disponibilità
1g 14,90
5g 47,70
25g 197,00
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1-Adamantanemethanol, 98%

MDL
MFCD00074751
EINECS
212-225-3

Proprietà chimiche

Formula
C11H18O
Peso formula
166.26
Punto di fusione
115-118°
Solubilità
Insoluble in water. Solubility in methanol (almost transparency).

Applicazioni

1-Adamantanemethanol was used in the synthesis of axially disubstituted silicon(IV) phthalocyanines. It is used as a reagent in the synthesis of adamantane and noradamantane based histone deacetylase (HDAC) inhibitors for the treatment of cancer. It is also used as a reagent in the synthesis of (1-adamantyl)methyl glycidyl ether, a versatile building block for living polymerization.

Note

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Letteratura

Shen X-M, et al. Highly photostable silicon (IV) phthalocyanines containing adamantane moieties: synthesis, structure, and properties. Tetrahedron.,2010,66(46), 9041-48.

A S Kostense, et al. Modeling and conformation analysis of beta-cyclodextrin complexes.J Comput Aided Mol Des.,1991,5(6), 525-43.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni precauzionali: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
1853339
Codice tariffe armonizzato
2906.19
TSCA
No

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