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5-Aminosalicylic acid is used in the preparation of gastrointestinal anti-inflammatory agents. It is a metabolite of sulfasalazine. It acts as a drug involved in the treatment of Crohns disease and ulcerative colitis. Further, it is used to make dyes and light-sensitive papers.
Bijani, S.; Jain, V.; Padmanabhan, D.; Pandey, B.; Shah, A. Mixed Pd/C and Pt/C as efficient catalysts for deuteration of Mesalamine. Tetrahedron Lett. 2015, 56 (10), 1211-1214.
Goyanes, A.; Buanz, A. B. M.; Hatton, G. B.; Gaisford, S.; Basit, A. W. 3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets. Eur. J. Pharm. Biopharm. 2015, 89, 157-162.
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.