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79651-64-2 - 2-Aminopyridine-6-methanol, 97% - 2-Amino-6-(hydroxymethyl)pyridine - H33485 - Alfa Aesar

H33485 2-Aminopyridine-6-methanol, 97%

Codice CAS
79651-64-2
Sinonimi
2-Amino-6-(hydroxymethyl)pyridine

Dimensioni Prezzo ($) Quantità Disponibilità
250mg 72,80
1g 202,00
5g 674,00
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2-Aminopyridine-6-methanol, 97%

MDL
MFCD09863097

Proprietà chimiche

Formula
C6H8N2O
Peso formula
124.14
Punto di fusione
87-92°
Solubilità
Slightly soluble.

Applicazioni

4-Aminopyridine (4-AP), a well-known potassium channel blocker, has been shown to enhance conduction in injured and demyelinated axons. Aminopyridine has a narrow therapeutic range in clinical application. In the current study, we investigated whether AP-MeOH can enhance impulse conduction in an animal model of MS.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Letteratura

Jinfeng Zhao,; Peng Song,; Yanling Cui,; Xuemei Liu,; Shaowu Sun,; Siyao Hou,; Fengcai Ma. Effects of hydrogen bond on 2-aminopyridine and its derivatives complexes in methanol solvent. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2015, 131 282-287.

Gary Leung,; Wenjing Sun,; Sarah Brookes,; Daniel Smith,; Riyi Shi. Potassium channel blocker, 4-aminopyridine-3-methanol, restores axonal conduction in spinal cord of an animal model of multiple sclerosis. Experimental Neurology. year of publication , 227 (1), 232-235.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.39
TSCA
No

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