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6188-23-4 - 6-Bromoimidazo[1,2-a]pyridine, 98% - H34453 - Alfa Aesar

H34453 6-Bromoimidazo[1,2-a]pyridine, 98%

Codice CAS
6188-23-4
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
1g 73,00
5g 240,00
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6-Bromoimidazo[1,2-a]pyridine, 98%

MDL
MFCD06496200

Proprietà chimiche

Formula
C7H5BrN2
Peso formula
197.03
Punto di fusione
78-80°
Solubilità
slightly soluble in water.

Applicazioni

It is used in organic syntheses and as pharmaceutical intermediates. The best results were obtained with lactams that could be introduced on the 6-bromoimidazo[1,2-a]pyridine. 1,2-dihydro-5-imidazo [1,2-a]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochloride monohydrate 6 was synthesized in 5 steps from 6-bromoimidazo[1,2-a] pyridine using [2- 14 C] cyanoacetamide as the source of the radiolabel.

Note

Incompatible with strong oxidizing agents. Store at room temperature.

Letteratura

Jamal Koubachi.; Saïd El Kazzouli.; Sabine Berteina-Raboin.; Abderrahim Mouaddib.; Gérald Guillaumet. Synthesis of Polysubstituted Imidazo[1,2-a]pyridines via Microwave-Assisted One-Pot Cyclization/Suzuki Coupling/Palladium-Catalyzed Heteroarylation.J. Org. Chem. 2007, 72 (20),7650-7655.

Giuseppe Trapani.; Massimo Franco.; Laura Ricciardi .; Andrea Latrofa.; Giuseppe Genchi.; Enrico Sanna.; Francesca Tuveri.; Elisabetta Cagetti.; Giovanni Biggio.; Gaetano Liso. Synthesis and Binding Affinity of 2-Phenylimidazo[1,2-a]pyridine Derivatives for both Central and Peripheral Benzodiazepine Receptors. A New Series of High-Affinity and Selective Ligands for the Peripheral Type. J. Med. Chem. 1997, 40 (19),3109-3118.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.99
TSCA
No

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