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553-03-7 - 3,4-Dihydro-2-(1H)-quinolinone, 98% - Hydrocarbostyril - H36638 - Alfa Aesar

H36638 3,4-Dihydro-2-(1H)-quinolinone, 98%

Codice CAS
553-03-7
Sinonimi
Hydrocarbostyril

Dimensioni Prezzo ($) Quantità Disponibilità
1g 40,50
5g 129,00
25g 431,00
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3,4-Dihydro-2-(1H)-quinolinone, 98%

MDL
MFCD00016722

Proprietà chimiche

Formula
C9H9NO
Peso formula
147.18
Punto di fusione
165-167°
Sensibilità
Light Sensitive
Solubilità
Slightly soluble in water.

Applicazioni

3,4-Dihydro-2-(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments. It is used to prepare potent bicyclic peptide deformylase inhibitors with antibacterial effects. It is also used to synthesize substituted iminopiperidines as inhibitors of human nitric oxide synthase isoforms.

Note

Light sensitive. Incompatible with oxidizing agents.

Letteratura

John J.Kilbane; Rajaram Ranganathan; Lisa Cleveland; Kevin J.Kayser; Claudia Ribiero; Monica M.Linhares. Selective removal of nitrogen from quinoline and petroleum by Pseudomonas ayucida IGTN9m. Appl Environ Microbiol. 2000, 66,(2), 688-693.

Takayuki Tsuritani; Yuhei Yamamoto; Masashi Kawasaki; Toshiaki Mase. Novel approach to 3,4-dihydro-2(1H)-quinolinone derivatives via cyclopropane ring expansion. Organic Letters. 2009, 11,(5), 1043-1045.

 

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H301-H315-H319-H317-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P363-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.49
TSCA
No

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