3-Chlorophenylmagnesium bromide is involved in the synthesis of enantiopure 2-imidazolidinones by reacting with 1,1'-DiBoc-2,2'-Biaziridine.
Murphy, C. L.; Hall, A.; Roberts, E. J.; Ryan, M. D.; Clary, J. W.; Singaram, B. Preparation and reactions of 4-iodobutyl pinacolborate. Synthesis of substituted alkyl and aryl pinacolboronates via 4-iodobutyl pinacolborate utilizing tetrahydrofuran as the leaving group. Tetrahedron Lett. 2015, 56 (23), 3032-3033.
Deane, K. J.; Summers, R. L.; Lehane, A. M.; Martin, R. E.; Barrow, R. A. Chlorpheniramine Analogues Reverse Chloroquine Resistance in Plasmodium falciparum by Inhibiting PfCRT. ACS Med. Chem. Lett. 2014, 5 (5), 576-581.
Dichiarazioni di rischio (UE): H225-H314-H318
Highly flammable liquid and vapour. Causes severe skin burns and eye damage. Causes serious eye damage.
Dichiarazioni precauzionali: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.