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51805-45-9 - Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water - TCEP HCl - H51864 - Alfa Aesar

H51864 Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water

Codice CAS
51805-45-9
Sinonimi
TCEP HCl

Dimensioni Prezzo ($) Quantità Disponibilità
5ml 39,04
25ml 158,62
100ml 400,00
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Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water

MDL
MFCD00145469

Proprietà chimiche

Formula
C9H15O6P•HCl
Peso formula
286.65
Solubilità
Miscible with water and methanol.

Applicazioni

Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

Note

Air sensitive. Store in cool place. Incompatible with strong oxidizing agents

Letteratura

La, M.; Feng, Y.; Yang, C.; Chen, C. Performances of p-Aminophenol Redox Cycling by Thiols and Tris (2-carboxyethyl) phosphine on Cysteamine-and 3-Mercaptopropionic acid-Covered Gold Electrodes. Int. J. Electrochem. Sci. 2014, 9, 6985-6992.

Miralles, G.; Verdie?, P.; Puget, K.; Maurras, A.; Martinez, J.; Subra, G. Microwave-mediated reduction of disulfide bridges with supported (Tris (2-carboxyethyl) phosphine) as resin-bound reducing agent. ACS Comb. Sci. 2013, 15 (4), 169-173.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H314

Causes severe skin burns and eye damage.

Dichiarazioni precauzionali: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Classe di rischio
8
Gruppo di imballaggio
III
Codice tariffe armonizzato
2931.90
TSCA
No

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