H52546 Phenanthrene-9-boronic acid, 97%
SDS
| Stock No. | Dimensioni | Prezzo ($) | Quantità | Disponibilità |
|---|---|---|---|---|
| H52546-03 | 1g | 41,20 |
|
|
| H52546-06 | 5g | 177,00 |
|
|
Phenanthrene-9-boronic acid, 97%
Proprietà chimiche
Applicazioni
Phenanthrene-9-boronic acid as a reactant is involved in the synthesis of large polycyclic aromatic hydrocarbons (PAHs) and electron rich benzo[g,h,i]perylenes. It is also used for preparation of FLAP protein inhibitors as anti-inflammatory agents and aminoisoquinolinones as PARP-2 selective inhibitors. As a reactant it is involved in homocoupling reactions.
Note
Letteratura
Tse-An Chen; Rai-Shung Liu. Synthesis of large polycyclic aromatic hydrocarbons from bis(biaryl)acetylenes: large planar PAHs with low π-sextets. Organic Letters. 2011, 13,(17), 4644-4647.
Rosa De Simone; Maria Giovanna Chini; Ines Bruno; Raffaele Riccio; Daniela Mueller; Oliver Werz; Giuseppe Bifulco. Structure-based discovery of inhibitors of microsomal prostaglandin E2 synthase-1, 5-lipoxygenase and 5-lipoxygenase-activating protein: promising hits for the development of new anti-inflammatory agents. Journal of medicinal and pharmaceutical chemistry. 2011, 54,(6), 1565-1575.
Rischio GHS e dichiarazioni precauzionali
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
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