Informativa e consenso per l'uso dei cookie

Accetto Il nostro sito salva piccoli pezzi di informazioni (cookie) sul dispositivo, al fine di fornire contenuti migliori e per scopi statistici. È possibile disattivare l'utilizzo di cookies modificando le impostazioni del tuo browser. Continuando la navigazione si acconsente all'utilizzo dei cookie.

68572-87-2 - Phenanthrene-9-boronic acid, 97% - H52546 - Alfa Aesar

H52546 Phenanthrene-9-boronic acid, 97%

Codice CAS
68572-87-2
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
1g 41,22
5g 157,60
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

Phenanthrene-9-boronic acid, 97%

MDL
MFCD00143524

Proprietà chimiche

Formula
C14H11BO2
Peso formula
222.05
Punto di fusione
254-256°
Solubilità
Soluble in DMSO.

Applicazioni

Phenanthrene-9-boronic acid as a reactant is involved in the synthesis of large polycyclic aromatic hydrocarbons (PAHs) and electron rich benzo[g,h,i]perylenes. It is also used for preparation of FLAP protein inhibitors as anti-inflammatory agents and aminoisoquinolinones as PARP-2 selective inhibitors. As a reactant it is involved in homocoupling reactions.

Note

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Letteratura

Tse-An Chen; Rai-Shung Liu. Synthesis of large polycyclic aromatic hydrocarbons from bis(biaryl)acetylenes: large planar PAHs with low π-sextets. Organic Letters. 2011, 13,(17), 4644-4647.

 

Rosa De Simone; Maria Giovanna Chini; Ines Bruno; Raffaele Riccio; Daniela Mueller; Oliver Werz; Giuseppe Bifulco. Structure-based discovery of inhibitors of microsomal prostaglandin E2 synthase-1, 5-lipoxygenase and 5-lipoxygenase-activating protein: promising hits for the development of new anti-inflammatory agents. Journal of medicinal and pharmaceutical chemistry. 2011, 54,(6), 1565-1575.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2931.90
TSCA
No

Raccomandato

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio