Informativa e consenso per l'uso dei cookie

Accetto Il nostro sito salva piccoli pezzi di informazioni (cookie) sul dispositivo, al fine di fornire contenuti migliori e per scopi statistici. È possibile disattivare l'utilizzo di cookies modificando le impostazioni del tuo browser. Continuando la navigazione si acconsente all'utilizzo dei cookie.

89343-06-6 - Triisopropylsilylacetylene, 97% - Ethynyltriisopropylsilane - H53405 - Alfa Aesar

H53405 Triisopropylsilylacetylene, 97%

Codice CAS
89343-06-6
Sinonimi
Ethynyltriisopropylsilane

Dimensioni Prezzo ($) Quantità Disponibilità
5g 55,52
25g 188,05
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

Triisopropylsilylacetylene, 97%

MDL
MFCD00075452

Proprietà chimiche

Formula
C11H22Si
Peso formula
182.38
Punto di ebollizione
50-52°/0.6mm
Punto di infiammabilità
56°(133°F)
Densità
0.813
Indice di rifrazione
1.4527
Solubilità
Miscible with organic solvents.

Applicazioni

Triisopropylsilylacetylene is used as a reagent for the rhodium-catalyzed asymmetric alkylation of alpha, beta-unsaturated carbonyl compounds as well as in the synthesis of beta-alkynylated nitroalkanes. It is utilized in the preparation of bromoethynyl-triisopropyl-silane in the presence of the reagents such as N-bromo succinimide and silver nitrate. It is actively in involved in Sonogashira coupling reaction with 1-bromo-3-iodo-5-tertbutylbenzene.

Note

Incompatible with strong acids, strong bases and strong oxidizing agents.

Letteratura

Sawano, T.; Ashouri, A.; Nishimura, T.; Hayashi, T. Cobalt-Catalyzed Asymmetric 1, 6-Addition of (Triisopropylsilyl)-acetylene to alfa, beta, gamma, delta-Unsaturated Carbonyl Compounds. J. Am. Chem. Soc. 2012, 134 (46), 18936-18939.

Li, Y.; Liu, L.; Kong, D.; Wang, D.; Feng, W.; Yue, T.; Li, C. Palladium-Catalyzed Alkynylation of Morita-Baylis-Hillman Carbonates with (Triisopropylsilyl)acetylene on Water. J. Org. Chem. 2015, 80 (12), 6283-6290.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H226-H315-H319-H335

Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P210-P261-P280-P240-P303+P361+P353-P305+P351+P338-P304+P340-P362-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
3536241
Classe di rischio
3
Gruppo di imballaggio
III
Codice tariffe armonizzato
2931.90
TSCA
No

Raccomandato

  • A10221

    Imidazole, 99%
  • A10588

    Tetra-n-butylammonium fluoride, 1M soln. in THF
  • A11766

    Allyl bromide, 99%, stab. with 300-1000ppm Propylene oxide
  • L06374

    Trifluoroacetic acid, 99%
  • H55205

    Tetra-n-butylammonium dichromate, 99%

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio