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3,4-Difluorophenylmagnesium bromide, 0.50 M in 2-MeTHF is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
Yunxiang Chen; Yangwei Huang; Xueqing Zhao; & Zhongming Lia. Concise Synthesis of 1,3-Diacetoxy-2-[2?-(2??,4??-difluorophenyl)prop-2?-en-1?-yl]propane: An Intermediate for Posaconazole. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 2015, 45 (6), 734-740.
Timothy A. Shepherd; James A. Aikins; David Bleakman; Buddy E. Cantrell; John P. Rearick; Richard L. Simon; Edward C. R. Smith; Gregory A. Stephenson; and Dennis M. Zimmerman. Design and Synthesis of a Novel Series of 1,2-Disubstituted Cyclopentanes as Small, Potent Potentiators of 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic Acid (AMPA) Receptors. J. Med. Chem. 2002, 45 (10), 2101-2111.
Dichiarazioni di rischio (UE): H225-H314-H318
Highly flammable liquid and vapour. Causes severe skin burns and eye damage. Causes serious eye damage.
Dichiarazioni precauzionali: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.