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156311-83-0 - (7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 99+% - PyAOP - H54378 - Alfa Aesar

H54378 (7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 99+%

Codice CAS
156311-83-0
Sinonimi
PyAOP

Dimensioni Prezzo ($) Quantità Disponibilità
1g 62,60
5g 250,00
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(7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 99+%

MDL
MFCD03703417

Proprietà chimiche

Formula
C17H27F6N7OP2
Peso formula
521.38
Punto di fusione
163-168°
Solubilità
Soluble in water.

Applicazioni

(7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate is used as reagent for synthesis of cyclic RGC pentapeptides for functionalization through click chemistry, fluorescent glucose bioprobes and ReactIR™ flow cell. It is also used as reagent for disulfide bond engineering, heteroaryl ether synthesis and optimization of conformational constraint on non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.

Note

Stable under recommended storage conditions. Store away from oxidizing agents.

Letteratura

Hyang Yeon Lee; Jae Jeong Lee; Jongmin Park; Seung Bum Park. Development of fluorescent glucose bioprobes and their application on real-time and quantitative monitoring of glucose uptake in living cells. Chemistry: A European Journal. 2011, 17, (1),143-150

 

Markus Muttenthaler; Asa Andersson; Aline D de Araujo; Zoltan Dekan; Richard J.Lewis; Paul F.Alewood. Modulating oxytocin activity and plasma stability by disulfide bond engineering. Journal of medicinal and pharmaceutical chemistry. 2010, 53, (24),8585-8596

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.99
TSCA
No
RTECS
TH3890000

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