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1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine per chlorate is a lipophilic dye used to record membrane voltage for fluidity studies. This retrograde stain is useful in staining neurons in vitro and in vivo because the stain is relatively nontoxic to cell bodies and the dye is retained in neurons. In addition, 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine per chlorate is an ideal retrograde and anterograde tracer to label the processes as well as the cell bodies of cultured neurons.
Beverly S. Packard.; David E. Wolf. Fluorescence lifetimes of carbocyanine lipid analogs in phospholipid bilayers.Biochemistry. 1985, 24 (19),5176-5181.
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.