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1575-61-7 - 5-Chlorovaleroyl chloride, 98% - H56237 - Alfa Aesar

H56237 5-Chlorovaleroyl chloride, 98%

Codice CAS
1575-61-7
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
50g 284,88
100g 486,34
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5-Chlorovaleroyl chloride, 98%

MDL
MFCD00000758
EINECS
216-403-1

Proprietà chimiche

Formula
C5H8Cl2O
Peso formula
155.02
Punto di ebollizione
38-39°
Punto di infiammabilità
91°(196°F)
Densità
1.2
Indice di rifrazione
1.464
Sensibilità
Moisture Sensitive
Solubilità
Reacts with water.

Applicazioni

5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine. It is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.

Note

Moisture sensitive. Incompatible with oxidizing agents, bases, alcohols, amines.

Letteratura

Liya Tang.; Alexandre Kim.; Scott A. Miller.; David K. Lloyd. Development and validation of a specific and sensitive GC-FID method for the determination of impurities in 5-chlorovaleroyl chloride.J. Pharm. Biomed. Anal. 2010, 53 (3), 309-314.

T. N. Kas’yanova.; A. D. Smolenkov.; A. V. Pirogov.; O. A. Shpigun. Effect of the acylating agent on the selectivity of anion-exchange resins and separation efficiency. Moscow University Chemistry Bulletin. 2007, 62 (5), 286-289.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H314-H318-H302-H227

Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if swallowed. Combustible liquid.

Dichiarazioni precauzionali: P210-P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
1745182
Classe di rischio
8
Gruppo di imballaggio
II
Codice tariffe armonizzato
2915.90
TSCA
No
RTECS
YV9108000

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