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21168-41-2 - Ethyl 4,6-dichloroquinoline-3-carboxylate, 97% - 4,6-Dichloroquinoline-3-carboxylic acid ethyl ester - H59231 - Alfa Aesar

H59231 Ethyl 4,6-dichloroquinoline-3-carboxylate, 97%

Codice CAS
21168-41-2
Sinonimi
4,6-Dichloroquinoline-3-carboxylic acid ethyl ester

Dimensioni Prezzo ($) Quantità Disponibilità
250mg 36,80
1g 118,00
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Ethyl 4,6-dichloroquinoline-3-carboxylate, 97%

MDL
MFCD00173348

Proprietà chimiche

Formula
C12H9Cl2NO2
Peso formula
270.11

Applicazioni

It is used as a pharmaceutical intermediate.

Note

Store at room temperature. Keep away from oxidizing agents.

Letteratura

Qingsong Liu.;Jae Won Chang.; Jinhua Wang.; Seong A. Kang.; Carson C. Thoreen.; Andrew Markhard.; Wooyoung Hur.; Jianming Zhang.; Taebo Sim.; David M. Sabatini.; Nathanael S. Gray. Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer. J. Med. Chem. 2010, 53 (19), 7146-7155.

Charles J. Paget.; Charles W. Ashbrook.; Robert Louis Stone.; Heterocyclic substituted ureas. III. Immunosuppressive and antiviral (2-pyrimidinyl)ureas. J. Med. Chem. 1969, 12 (6),1097-1098.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.49
TSCA
No

Raccomandato

  • H50503

    Ethyl 4-chloro-6,8-difluoroquinoline-3-carboxylate
  • H50507

    Ethyl 4-chloro-8-fluoroquinoline-3-carboxylate, 97%
  • H50509

    Ethyl 4-chloro-8-methoxyquinoline-3-carboxylate
  • H50514

    Ethyl 4-chloro-5,7-difluoroquinoline-3-carboxylate, 99%
  • H50515

    Ethyl 4-chloro-6-methoxyquinoline-3-carboxylate, 97%

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