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59382-59-1 - Methyl 2-methyl-3-nitrobenzoate, 97% - Methyl 3-nitro-o-toluate - 2-Methyl-3-nitrobenzoic acid methyl ester - H60242 - Alfa Aesar

H60242 Methyl 2-methyl-3-nitrobenzoate, 97%

Codice CAS
59382-59-1
Sinonimi
Methyl 3-nitro-o-toluate
2-Methyl-3-nitrobenzoic acid methyl ester

Dimensioni Prezzo ($) Quantità Disponibilità
5g 28,44
25g 115,20
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Methyl 2-methyl-3-nitrobenzoate, 97%

MDL
MFCD00082564

Proprietà chimiche

Formula
C9H9NO4
Peso formula
195.17
Punto di fusione
62-65°
Solubilità
Soluble in methanol.

Applicazioni

Methyl 2-methyl-3-nitrobenzoate may be used in the synthesis of methyl indole-4-carboxylate, 5-aminoisoquinolin-1(2H)-one, 5-nitroisocoumarin and [2-(4-fluorophenyl)-1H-indol-4-yl]-1-pyrrolidinylmethanone. It may also be used in the preparation of substituted nitrostyrene benzoic acids, via reaction with aromatic aldehydes in the presence of DBU in DMSO; and 4-(hydroxymethyl)-1-tosylindole, via Batcho-Leimgruber modification of the Reissert indole synthesis.

Note

Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

Letteratura

M.C.McDonald; H.Mota-Filipe; J.A.Wright; M.Abdelrahman; M.D.Threadgill; A.S.Thompson; C.Thiemermann. Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock. British Journal of Pharmacology. 2000, 130,(4), 843-850.

 

A.N.Brubaker; M.Colley. Synthesis and pharmacological evaluation of some 6-substituted 7-methyl-1,4-dioxa-7-azaspiro[4.5]decanes as potential dopamine agonists. Journal of Medicinal Chemistry. 1986, 29,(8), 1528-1531.

Altri riferimenti

Beilstein
1964020
Codice tariffe armonizzato
2916.39
TSCA
No

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