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478-43-3 - Rhein, 97% - 4,5-Dihydroxyanthraquinone-2-carboxylic acid - H60902 - Alfa Aesar

H60902 Rhein, 97%

Codice CAS
478-43-3
Sinonimi
4,5-Dihydroxyanthraquinone-2-carboxylic acid

Dimensioni Prezzo ($) Quantità Disponibilità
250mg 149,00
1g 425,00
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Rhein, 97%

MDL
MFCD00009618
EINECS
207-521-4

Proprietà chimiche

Formula
C15H8O6
Peso formula
284.22
Punto di fusione
>300°
Solubilità
Soluble in sodium hydroxide. Insoluble in water, dimethylsulfoxide and ethanol.

Applicazioni

Rhein is used to inhibit growth factor beta-1 induced plasminogen activator inhibitor-1 in endothelial cells. It acts as an antibacterial agent against Staphylococcus aureus. It is also used as a laxative. Further, it is employed as a pharmaceutical intermediate.

Note

Incompatible with oxidizing agents. Heat sensitive.

Letteratura

Li, J.; Dong, N.; Cheng, S.; Li, X.; Wang, W.; Xiang, Y. Tetramethylpyrazine inhibits CTGF and Smad2/3 expression and proliferation of hepatic stellate cells. Biotechnol. Biotechnol. Equip. 2015, 29 (1), 124-131.

Qu, H.; Wang, Y.; Shan, W.; Zhang, Y.; Feng, H.; Sai, J.; Wang, Q.; Zhao, Y. Development of ELISA for detection of Rh1 and Rg2 and potential method of immunoaffinity chromatography for separation of epimers. J. Chromatogr. B 2015, 985, 197-205.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
2222155
Codice tariffe armonizzato
2918.99
TSCA
No
RTECS
CA9516000

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