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478-43-3 - Rhein, 97% - 4,5-Dihydroxyanthraquinone-2-carboxylic acid - H60902 - Alfa Aesar

H60902 Rhein, 97%

Codice CAS
478-43-3
Sinonimi
4,5-Dihydroxyanthraquinone-2-carboxylic acid

Dimensioni Prezzo ($) Quantità Disponibilità
250mg 150,38
1g 417,00
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Rhein, 97%

MDL
MFCD00009618
EINECS
207-521-4

Proprietà chimiche

Formula
C15H8O6
Peso formula
284.22
Punto di fusione
>300°
Solubilità
Soluble in sodium hydroxide. Insoluble in water, dimethylsulfoxide and ethanol.

Applicazioni

Rhein is used to inhibit growth factor beta-1 induced plasminogen activator inhibitor-1 in endothelial cells. It acts as an antibacterial agent against Staphylococcus aureus. It is also used as a laxative. Further, it is employed as a pharmaceutical intermediate.

Note

Incompatible with oxidizing agents. Heat sensitive.

Letteratura

Li, J.; Dong, N.; Cheng, S.; Li, X.; Wang, W.; Xiang, Y. Tetramethylpyrazine inhibits CTGF and Smad2/3 expression and proliferation of hepatic stellate cells. Biotechnol. Biotechnol. Equip. 2015, 29 (1), 124-131.

Qu, H.; Wang, Y.; Shan, W.; Zhang, Y.; Feng, H.; Sai, J.; Wang, Q.; Zhao, Y. Development of ELISA for detection of Rh1 and Rg2 and potential method of immunoaffinity chromatography for separation of epimers. J. Chromatogr. B 2015, 985, 197-205.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
2222155
Codice tariffe armonizzato
2918.99
TSCA
No
RTECS
CA9516000

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