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31224-43-8 - 3-Fluoropyridine-2-carboxaldehyde, 98% - 3-Fluoro-2-formylpyridine - 3-Fluoropicolinaldehyde - H61902 - Alfa Aesar

H61902 3-Fluoropyridine-2-carboxaldehyde, 98%

Codice CAS
31224-43-8
Sinonimi
3-Fluoro-2-formylpyridine
3-Fluoropicolinaldehyde

Dimensioni Prezzo ($) Quantità Disponibilità
250mg 23,04
1g 69,12
5g 356,38
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3-Fluoropyridine-2-carboxaldehyde, 98%

MDL
MFCD07781234

Proprietà chimiche

Formula
C6H4FNO
Peso formula
125.10
Solubilità
Slightly soluble in water.

Applicazioni

3-Fluoropyridine-2-carboxaldehyde is used to prepare taxoids derived from 9β-dihydrobaccatin-9,10-acetals with anti-tumor activities. It is also an intermediate used to synthesize S-3578 derivatives with potent activities against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa.

Note

Store in cool, well ventilated area. Keep container tightly closed. Store away from oxidizing agent.

Letteratura

Christopher M. Timperley; R. Eric Banks; Ian M. Young; Robert N. Haszeldine. Synthesis of some fluorine-containing pyridinealdoximes of potential use for the treatment of organophosphorus nerve-agent poisoning. Journal of Fluorine Chemistry. 2011, 132(8), 541-547.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.39
TSCA
No

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