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Thiazole-2-carboxaldehyde may be used as a reactant in the following syntheses Benzothiazine N-acylhydrazones, having potential antinociceptive and anti-inflammatory activity, Thiazole-2-yl-(amino)methylphosphonate diethyl esters, Imino ester by reacting with L-leucine t-butyl ester hydrochloride. Also used in building block for taxane analogs.
Amanda Silva de Miranda et. al. Design, synthesis, antinociceptive and anti-inflammatory activities of novel piroxicam analogues. Molecules. 2005, 17 (12), 14126-14145.
Olszewski TK; and Boduszek B. Synthesis of new thiazole-2,-4, and-5-yl-(amino) methylphosphonates and phosphinates: unprecedented cleavage of thiazole-2 derivatives under acidic conditions. Tetrahedron. 2010, 66 (45), 8661-866.
Dichiarazioni di rischio (UE): H227-H315-H319-H335
Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P260-P201-P280a-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves and eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.