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22282-72-0 - 2-Hydroxypyridine-4-carboxylic acid, 98% - 2-Hydroxyisonicotinic acid - H64241 - Alfa Aesar

H64241 2-Hydroxypyridine-4-carboxylic acid, 98%

Codice CAS
22282-72-0
Sinonimi
2-Hydroxyisonicotinic acid

Dimensioni Prezzo ($) Quantità Disponibilità
5g 35,30
25g 141,00
100g 564,00
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2-Hydroxypyridine-4-carboxylic acid, 98%

MDL
MFCD01318566

Proprietà chimiche

Formula
C6H5NO3
Peso formula
139.11

Applicazioni

Used in the synthesis of selective inhibitors of neuropeptide Y Y5 inhibiting food intake. Also used in the optimization of p-subsite residues of HIV protease inhibitors.

Note

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Letteratura

Ando, M. et al. Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor. Bioorganic & Medicinal Chemistry. 2009 17(16), 6106-6122.

Ashraf Brik; Ying-Chuan Lin; John Elder; Chi-Huey Wong. A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors. Chem. Biol. 2002 9(8), 891-896.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
115859
Codice tariffe armonizzato
2933.39
TSCA
No

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