Useful synthetic intermediate. It can be used to prepare potent and orally available G protein-coupled receptor 40 agonists as potential antidiabetic agents. May be used in the enzymatic coupling of saccharides to protein.
Ruud ter Haar et. al. Proof of principle for the synthesis of hydroxy-aryl esters of glycosidic polyols and non-reducing oligosaccharides with subsequent enzymatic coupling to a tyrosine-containing tripeptide. Carbohydrate Research. 2011 346(8), 1005-1012.
Hossain A K M Zakir; Guntur V Subbarao; Stuart J Pearse; Subramaniam Gopalakrishnan; Osamu Ito; Takayuki Ishikawa; Naoyoshi Kawano; Kazuhiko Nakahara; Tadashi Yoshihashi; Hiroshi Ono; Mitsuru Yoshida. Detection, isolation and characterization of a root-exuded compound, methyl 3-(4-hydroxyphenyl) propionate, responsible for biological nitrification inhibition by sorghum (Sorghum bicolor). New Phytologist.2008 180(2), 442-451.
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.