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1546-78-7 - 4-Hydroxy-6-(trifluoromethyl)pyrimidine, 97% - 6-(Trifluoromethyl)-4-pyrimidinol - H64381 - Alfa Aesar

H64381 4-Hydroxy-6-(trifluoromethyl)pyrimidine, 97%

Codice CAS
1546-78-7
Sinonimi
6-(Trifluoromethyl)-4-pyrimidinol

Dimensioni Prezzo ($) Quantità Disponibilità
1g 21,40
5g 103,00
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4-Hydroxy-6-(trifluoromethyl)pyrimidine, 97%

MDL
MFCD00192530

Proprietà chimiche

Formula
C5H3F3N2O
Peso formula
164.09
Punto di fusione
169-171°
Solubilità
Solubility in methanol (almost transparency). Slightly soluble in water.

Applicazioni

6-(Trifluoromethyl)-4-pyrimidinol is used as building block in chemical synthesis. It may also be used in the synthesis of 10-[3-(6-trifluoromethyl-pyrimidin-4-yloxy)-propoxy]-(20S)-camptothecin.

Note

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Protect from heat.

Letteratura

Qingyong Li, et al. Synthesis and antitumor activity of novel 10-substituted camptothecin analogues.Bioorg Med Chem.,2006,14(21), 7175-7182.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
145548
Codice tariffe armonizzato
2933.59
TSCA
No

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