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2075-45-8 - 4-Bromo-1H-pyrazole, 98+% - H64673 - Alfa Aesar

H64673 4-Bromo-1H-pyrazole, 98+%

Codice CAS
2075-45-8
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
25g 31,80
500g 269,00
1kg 449,00
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4-Bromo-1H-pyrazole, 98+%

MDL
MFCD00075602

Proprietà chimiche

Formula
C3H3BrN2
Peso formula
146.97
Punto di fusione
93-96° lit.
Punto di ebollizione
250-260° lit.
Solubilità
Slightly soluble in water.

Applicazioni

4-Bromopyrazole may be used in the preparation of 4-bromo-1-(2-chloroethyl)-1H-pyrazole. It may be used as starting material in the synthesis of 1,4?-bipyrazoles. Also used in the synthesis of various pharmaceutical and biologically active compounds, including inhibitors. It is also shown to be one of the 4-substituted pyrazoles, being able to act as inhibitor of liver alcohol dehydrogenase.

Note

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Letteratura

Guzei IA; and Winter CH. Structural Diversity in the Reaction of Mono- and Disubstituted Pyrazoles with Titanium Tetrachloride. Importance of Hydrogen Bonding and Trends in cis/trans Geometry of Binary Adducts with Unidentate Ligands. Inorg. Chem. 1997 36(20), 4415-4420.

E Alejandre-Durán; M Ruiz-Rubio; R M Claramunt; C López; C Pueyo. Mutagenicity study on pyrazole, seven pyrazole derivatives, and two nitroimidazoles with the L-arabinose resistance test of Salmonella typhimurium. Environmental Mutagenesis.1986 8(4), 611-619.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
106510
Codice tariffe armonizzato
2933.19
TSCA
No
RTECS
UQ6200000

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