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80194-69-0 - 5-(Trifluoromethyl)pyridine-2-carboxylic acid, 95% - 5-(Trifluoromethyl)picolinic acid - H64937 - Alfa Aesar

H64937 5-(Trifluoromethyl)pyridine-2-carboxylic acid, 95%

Codice CAS
80194-69-0
Sinonimi
5-(Trifluoromethyl)picolinic acid

Dimensioni Prezzo ($) Quantità Disponibilità
1g 28,43
5g 114,33
25g 460,00
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5-(Trifluoromethyl)pyridine-2-carboxylic acid, 95%

MDL
MFCD04113632

Proprietà chimiche

Formula
C7H4F3NO2
Peso formula
191.11
Punto di fusione
133-137°
Solubilità
Slightly soluble in water.

Applicazioni

5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.

Note

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Letteratura

Roger Crettaz; Jérôme Waser; and Yves Bessard. Synthetic Process Development and Scale Up of Palladium-Catalyzed Alkoxycarbonylation of Chloropyridines. Org. Proc. Res. Dev.2001 5(6), 572-574.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.39
TSCA
No

Raccomandato

  • A10226

    2-(Chloromethyl)pyridine hydrochloride, 98%
  • A12775

    1,2-Dichloroethane, 99+%
  • H30923

    5-Chloropyridine-2-carboxylic acid, 95%
  • 41868

    Thionyl chloride, 99+%
  • H64499

    5-Nitropyridine-2-carboxylic acid, 97+%

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