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N-Lauroylsarcosine is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase. It is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming). It has been used to indicate paramagnetic anisotropy sign change in micelle mesophage. Inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%).
P Gariglio; J Buss; M H Green. Sarkosyl activation of RNA polymerase activity in mitotic mouse cells. FEBS Letters, 1974, 44(3), 330-333.
R J MacDonald; G H Swift; A E Przybyla; J M Chirgwin. Isolation of RNA using guanidinium salts. Methods in Enzymology, 1987 152 219-227.
Dichiarazioni di rischio (UE): H330-H315-H318
Fatal if inhaled. Causes skin irritation. Causes serious eye damage.
Dichiarazioni precauzionali: P260-P304+P340-P305+P351+P338-P320-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.