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474-25-9 - Chenodeoxycholic acid - J60364 - Alfa Aesar

J60364 Chenodeoxycholic acid

Codice CAS
474-25-9
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
5g 65,10
25g 198,00
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Chenodeoxycholic acid

MDL
MFCD00064142
EINECS
207-481-8

Proprietà chimiche

Formula
C24H40O4
Peso formula
392.57
Modulo
Needle crystals
Punto di fusione
164-168°
Solubilità
Soluble in water, dimethyl sulfoxide, ethanol and dimethylformamide.

Applicazioni

Chenodeoxycholic acid is a bile acid that induces apoptosis through protein kinase C signaling pathways.Chenodeoxycholic acid is widely utilized in therapeutic applications. It is applied in medical therapy to dissolve gallstones. It is employed in the treatment of cerebrotendineous xanthomatosis. It is used to treat constipation and cerebrotendineous xanthomatosis. It acts as a urea receptor in supramolecular chemistry which can contain anions. It is a staining additive commonly used with ruthenium or organic photo-sensitizers in the preparation of staining solutions for dye solar cells.

Note

Incompatible with strong oxidizing agents.

Letteratura

Zhang, Y.; Qu, H.; Feng, H.; Wang, X.; Shan, W.; Zeng, W.; Wang, Q.; Zhao, Y. Development of an enzyme-linked immunosorbent assay for chenodeoxycholic acid using an anti-chenodeoxycholic acid monoclonal antibody. Anal. Methods 2015, 7 (11), 4583-4589.

Jones, R. D.; Lopez, A. M.; Tong, E. Y.; Posey, K. S.; Chuang, J. C.; Repa, J. J.; Turley, S. D. Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice. Steroids 2015, 93, 87-95.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H303-H361

May be harmful if swallowed. Suspected of damaging fertility or the unborn child.

Dichiarazioni precauzionali: P201-P280-P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,2054
Beilstein
3219887
Codice tariffe armonizzato
2918.19
TSCA
No
RTECS
FZ1980000

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