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10592-13-9 - Doxycycline hydrochloride - J60422 - Alfa Aesar

J60422 Doxycycline hydrochloride

Codice CAS
10592-13-9
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
1g 42,50
5g 74,60
25g 298,00
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Doxycycline hydrochloride

MDL
MFCD03427564
EINECS
234-198-7

Proprietà chimiche

Formula
C22H24N2O8•HCl
Peso formula
480.90
Modulo
Crystalline powder
Punto di fusione
195-201°
Solubilità
Soluble in water to 50mg/ml. May require warming.

Applicazioni

Inhibits angiogenesis and reduces lung metastases by inhibiting matrix metalloproteinases.Doxycycline hydrochloride is an antibiotic used to inhibit matrix metalloproteinases like type 1 collagenase in studies on would healing and tissue remodeling. It shows the broad spectrum antibacterial and antiprotozoan activity. It is often used to treat lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease acne, rosacea, and rickettsial infections and prophylaxis of anthrax.

Note

Research Use only: Not intended for animal or human diagnostic or therapeutic use.Incompatible with strong oxidizing agents.

Letteratura

Gad, H. A.; Kamel, A. O.; Sammour, O. A.; Dessouky, H. F. E. Vesicular powder as carrier for doxycycline hydrochloride and metronidazole combination therapy. Pharm. Dev. Technol. 2014, 19 (6), 755-768.

Yang, S.; Li, K. Dissolution profile study on the novel doxycycline hydrochloride sustained-release capsules. Pak. J. Pharm. Sci. 2014, 27 (5), 1615-1620.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2941.30
TSCA
No

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