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Carboplatin is primarily used as an antitumor agent.Carboplatin is widely utilized as a chemotherapy drug to treat various types of cancer. It belongs to the group of platinum-based antineoplastic agents to interfere in DNA (deoxyribonucleic acid) repair. It is applied in combination other medications and used to inhibit cancer cell growth.
Jakacki, R. I.; Burger, P. C.; Kocak, M.; Boyett, J. M.; Goldwein, J.; Mehta, M.; Packer, R. J.; Tarbell, N. J.; Pollack, I. F. Outcome and Prognostic Factors for Children With Supratentorial PrimitiveNeuroectodermal Tumors Treated With Carboplatin During Radiotherapy:A Report from the Childrens Oncology Group. Pediatr Blood Cancer 2015, 62 (5), 776-783.
Boal, A. K.; Rosenzweig, A. C. Response from Boal and Rosenzweig to Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin. Acta Crystallogr., Sect. D: Biol. Crystallogr. 2015, 71, 1984-1986.
Dichiarazioni di rischio (UE): H302-H312-H332-H334-H317-H340-H360
Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. May cause genetic defects. May damage fertility or the unborn child.
Dichiarazioni precauzionali: P284-P201-P261-P280-P405-P501a
Wear respiratory protection. Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.