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31282-04-9 - Hygromycin B - J60681 - Alfa Aesar

J60681 Hygromycin B

Codice CAS
31282-04-9
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
100mg 71,48
250mg 86,40
1g 129,78
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Hygromycin B

MDL
MFCD06795479
EINECS
250-545-5

Proprietà chimiche

Formula
C20H37N3O13
Peso formula
527.53
Modulo
Lyophilized powder
Solubilità
Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents.

Applicazioni

An aminoglycoside antibiotic that kills bacteria by inhibiting protein synthesisHygromycin B is used for the selection and maintenance of prokaryotic and eukaryotic cells that contains the hygromycin resistance gene. This gene is frequently used as a selectable marker in research on plants. It stabilizes the transfer ribonucleic acid (tRNA)-ribosomal acceptor site, thereby inhibiting translocation. In addition to this, it serves as an aminoglycosidic antibiotic which inhibits protein synthesis.

Note

Research Use only: Not intended for animal or human diagnostic or therapeutic use.Incompatible with strong oxidizing agents.

Letteratura

Chen, C. F.; Chan, K. G.; Tan, B. C.; Khalid, N. Enhancement of Agrobacterium-mediated transformation efficiency of model plant using quorum sensing molecule, N-3-oxo-octanoyl-l-homoserine-lactone. Plant Cell Tissue Organ Cult. 2015, 121 (2), 481-487.

Park, Y.; Hosomichi, J.; Ge, C.; Xu, J.; Franceschi, R.; Kapila, S. Immortalization and characterization of mouse temporomandibular joint disc cell clones with capacity for multi-lineage differentiation. Osteoarthr. Cartil. 2015, 23 (9), 1532-1542.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H300-H310-H330-H317-H334-H318

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes serious eye damage.

Dichiarazioni precauzionali: P260-P284-P301+P310-P304+P340-P305+P351+P338-P320-P330-P361-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Rinse mouth. Remove/Take off immediately all contaminated clothing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,4852
Classe di rischio
6.1
Gruppo di imballaggio
I
Codice tariffe armonizzato
2941.90
TSCA
No
RTECS
WK2130000

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