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1257-08-5 - (-)-Epicatechin gallate - (-)-cis-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate - ECG - J60814 - Alfa Aesar

J60814 (-)-Epicatechin gallate

Codice CAS
1257-08-5
Sinonimi
(-)-cis-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate
ECG

Dimensioni Prezzo ($) Quantità Disponibilità
10mg 154,00
20mg 283,00
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(-)-Epicatechin gallate

MDL
MFCD00075936

Proprietà chimiche

Formula
C22H18O10
Peso formula
442.37
Modulo
Powder
Solubilità
Soluble in water, acetone, DMSO, methanol.

Applicazioni

(-)-Epicatechin gallate is used as an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C

Letteratura

SJ Baek.; JS Kim.; FR Jackson.; TE Eling. Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. Carcinogenesis . 2015, 25,(12), S254-S296.

CT Ho.; Q Chen.; H Shi.; KQ Zhang.; RT Rosen. Antioxidative effect of polyphenol extract prepared from various Chinese teas. Preventive medicine . 1992, 21,(4), 520-525.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni precauzionali: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2932.99
TSCA
No
RTECS
DH9030000

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