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13292-46-1 - Rifampin, Molecular Biology Reagent - Rifampicin - J60836 - Alfa Aesar

J60836 Rifampin, Molecular Biology Reagent

Codice CAS
13292-46-1
Sinonimi
Rifampicin

Dimensioni Prezzo ($) Quantità Disponibilità
1g 31,40
5g 113,00
25g 313,00
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Rifampin, Molecular Biology Reagent

MDL
MFCD00151389
EINECS
236-312-0

Proprietà chimiche

Formula
C43H58N4O12
Peso formula
822.94
Modulo
Powder
Punto di fusione
183-188°
Solubilità
Soluble in DMSO or methanolSoluble in water, ethyl acetate, chloroform, methanol, tetrahydrofuran and dimethyl sulfoxide.

Applicazioni

Antibiotic effective against mycobacteria. Can also inhibit DNA polymeraseRifampin is an antibiotic used in the treatment of tuberculosis and its related microbacterial infections. It is involved in the inhibition of DNA polymerase and RNA polymerase. As an antipruritic agent, it is used in the autoimmune cholestatic liver disease and primary biliary cirrhosis (PBC).

Note

Research Use only: Not intended for animal or human diagnostic or therapeutic use.Light sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Letteratura

Yakrus, M. A.; Driscoll, J.; Lentz, A. J.; Sikes, D.; Hartline, D.; Metchock, B.; Starks, A. M. Concordance between molecular and phenotypic testing of Mycobacterium tuberculosis complex isolates for resistance to rifampin and isoniazid in the United States. J. Clin. Microbiol. 2014, 52 (6), 1932-1937.

Baciewicz, A. M.; Chrisman, C. R.; Finch, C. K.; Self, T. H. Update on rifampin, rifabutin, and rifapentine drug interactions. Curr. Med. Res. Opin. 2013, 29 (1), 1-12.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,8216
Beilstein
5723476
Codice tariffe armonizzato
2941.90
TSCA
No
RTECS
VJ7000000

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