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4474-91-3 - Angiotensin II (human) - H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt - J60866 - Alfa Aesar

J60866 Angiotensin II (human)

Codice CAS
4474-91-3
Sinonimi
H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt

Dimensioni Prezzo ($) Quantità Disponibilità
5mg 47,90
25mg 164,00
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

Angiotensin II (human)

MDL
MFCD00133092

Proprietà chimiche

Formula
C50H71N13O12
Peso formula
1046.19
Modulo
Powder
Solubilità
Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).

Applicazioni

Ang II stimulates angiogenesis and increases microvessel density. In addition, the renin-angiotensin and nitric oxide-generating systems appear to interract in the regulation of cardiovascular function. Angiotensin (Ang) II is a peptide which plays an important role in the regulation of blood pressure and has strong vasoconstrictive effects. It also stimulates the release of aldosterone from the adrenal gland and inhibits adenylate cyclase activity. It also increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase (MYLK). It also elicits an increase in voltage-dependent delayed rectifier K+ current in neurons and activates JAK2 in smooth muscle cells.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C. keep away from Strong acids, Strong bases .

Letteratura

Caroline Cheng et. Al. Angiotensin II (ATII)-mediated hypertension increases the risk for acute coronary events, which may be caused by augmented collagen degradation. Interstitial fibers of collagen type I in the plaque can be degraded by MMP8 and MMP13 specifically. Atherosclerosis . 2009, 204,(1), 26-33.

Hsiang-Hao Hsu et. Al. Mechanisms of angiotensin II signaling on cytoskeleton of podocytes. Journal of Molecular Medicine . 2008, 86,(12), 1379-1394.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni precauzionali: P260-P201-P280-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2937.19
TSCA
No
RTECS
BW2165000

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