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Thioridazine is a piperidine typical antipsychotic drug belonging to the phenothiazine widely used in the treatment of schizophrenia and psychosis. It primary use in medicine was the treatment of schizophrenia.This medication is used to treat certain mental/mood disorders (e.g., schizophrenia). Thioridazine·HCl is a calcium channel protein inhibitor as well as a D2DR/D4DR inhibitor. It is an intercalating agent for analyzing the integrity of double stranded DNA by using the square-wave voltammetry.
H. Garfield Kelly,; J. E. Fay,; S. G. Laverty.Thioridazine Hydrochloride (Mellaril): Its Effect on the Electrocardiogram and a Report of Two Fatalities with Electrocardiographic Abnormalities. Can Med Assoc J. 1963, 89 (11), 546-554.
John R. Huston, MD; George E. Bell, MD.The Effect of Thioridazine Hydrochloride and Chlorpromazine on the Electrocardiogram. JAMA. 1966, 198 (1), 16-20..
Dichiarazioni di rischio (UE): H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.