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145-73-3 - Endothall - 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid - J60948 - Alfa Aesar

J60948 Endothall

Codice CAS
145-73-3
Sinonimi
7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid

Dimensioni Prezzo ($) Quantità Disponibilità
100mg 349,17
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Endothall

MDL
MFCD00137362
EINECS
205-660-5

Proprietà chimiche

Formula
C8H10O5
Peso formula
186.20
Modulo
Powder
Solubilità
Soluble in water (>25 mg/ml), methanol, acetone, and DMSO. Insoluble in benzene.

Applicazioni

Endothall is used as an inhibitor of PP2A phosphatase activity. It is also used as a defoliant. It is used as a cell adhesion inhibitor.

Note

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 12 months.

Letteratura

F Erdodi.; B Toth.; K Hirano.; M Hirano. Endothall thioanhydride inhibits protein phosphatases-1 and-2A in vivo. American Journal of Physiology - Cell Physiology. 1995, 269 ,(5), C1176-C1184.

YM Li.; C Mackintosh.; JE Casida. Protein phosphatase 2A and its [3 H] cantharidin/[3 H] endothall thioanhydride binding site: Inhibitor specificity of cantharidin and ATP analogues. Biochemical pharmacology. 1993, 46 ,(8), 1435-1443.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H301-H312-H315-H319-H335

Toxic if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P363-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,3575
Classe di rischio
6.1
Gruppo di imballaggio
II
Codice tariffe armonizzato
2932.19
TSCA
No
RTECS
RN7875000

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