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512-04-9 - Diosgenin - 3-beta-Hydroxy-5-spirostene - Nitogenin - J60976 - Alfa Aesar

J60976 Diosgenin

Codice CAS
512-04-9
Sinonimi
3-beta-Hydroxy-5-spirostene
Nitogenin

Dimensioni Prezzo ($) Quantità Disponibilità
5g 34,40
25g 103,00
100g 287,00
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Diosgenin

MDL
MFCD00016887
EINECS
208-134-3

Proprietà chimiche

Formula
C27H42O3
Peso formula
414.63
Modulo
Powder
Punto di fusione
200-206°
Solubilità
Soluble in chloroform (50 mg/ml), ethanol (83 mg/ml at 25°C), water (<1 mg/ml at 25°C), DMSO (<1 mg/ml at 25°C), and methanol.

Applicazioni

Diosgenin is the precursor for the semisynthesis of progesterone which in turn was used in early combined oral contraceptive pills. The unmodified steroid has estrogenic activity and can reduce the level of serum cholesterol. Diosgenin has been used in traditional medicine as an antihypercholesterolemia, antihypertriacylglycerolemia, antidiabetes and antihyperglycemia agent. Diosgenin is a steroid sapogenin used in the semi-synthesis of pregnenolone, cortisone, and progesterone. Diosgenin has estrogenic activity and can reduce the level of serum cholesterol.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Letteratura

Pin-Shern Chen,; Yuan-Wei Shih,; Hsiang-Ching Huang,; Hsing-Wen Cheng. Diosgenin, a Steroidal Saponin, Inhibits Migration and Invasion of Human Prostate Cancer PC-3 Cells by Reducing Matrix Metalloproteinases Expression. PLoS ONE. 2011, 6 (5), e20164.

Heena J Shah,; Lele SS. Extraction of Diosgenin, a Bioactive Compound from Natural Source Dioscorea alata Var purpurae. Shah and Lele, J Anal Bioanal Techniques. 2014, 3 (4)

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni precauzionali: P260-P201-P280-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,3295
Beilstein
94582
Codice tariffe armonizzato
2932.99
TSCA
No
RTECS
WH1450000

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