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Ampicillin is used as asemi-synthetic antibiotic which has antibacterial activity structurally related to penicillin. It is widely used selection reagent for transformed cells expressing β-lactamase. It is also used to prevent and treat a number of bacterial infections. It may also be used to prevent group B streptococcal infection in newborns.
An ampicillin stock solution can be prepared at a concentration of 50 mg/mL in 1M NH4OH and should be stored at -20⁰C.
LB-ampicillin agar preparation:
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Zhao Z., Baldo BA., O'Brien RM., Plomley RF. Reaction with, and fine structural recognition of polyamines by human IgE antibodies. Molecular immunology . 2000, 37,(5), 233-240.
Harmoinen J., Vaali K., Koski P., Syrjänen K., Laitinen O., Lindevall K., Westermarck E. Enzymic degradation of a beta-lactam antibiotic, ampicillin, in the gut: a novel treatment modality. The Journal of antimicrobial chemotherapy . 2003, 51,(2), 361-365.
Dichiarazioni di rischio (UE): H315-H319-H334-H317-H335
Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. May cause respiratory irritation.
Dichiarazioni precauzionali: P284-P261-P280a-P305+P351+P338-P405-P501a
Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.