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58-58-2 - Puromycin dihydrochloride, 99% - J61278 - Alfa Aesar

J61278 Puromycin dihydrochloride, 99%

Codice CAS
58-58-2
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
25mg 49,70
100mg 162,00
500mg 597,00
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Puromycin dihydrochloride, 99%

MDL
MFCD00012691
EINECS
200-387-8

Proprietà chimiche

Formula
C22H29N7O5•2HCl
Peso formula
544.44
Modulo
Powder
Punto di fusione
168-170°
Solubilità
Soluble in water

Applicazioni

It also exhibits antitumor activity in studies on brain tumor cells. Puromycin is a protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3¢-terminal end of aminoacyl-tRNA. It has been used to study transcriptional regulatory mechanisms that control the sequential and coordinate expression of genes during cell differentiation.

Note

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Letteratura

RA Rosson.; BM Tebo.; KH Nealson. Use of poisons in determination of microbial manganese binding rates in seawater. Appl. Environ. Microbiol. 1984, 47,(7), 740-745.

V Nair.; DJ Emanuel. Synthetic design, stereochemistry, and enzymic activity of a reversed aminoacyl nucleoside: an analog of puromycin. J. Am. Chem. Soc. 1977, 99,(5), 1571-1576.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302

Harmful if swallowed.

Dichiarazioni precauzionali: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,7943
Beilstein
3853613
Codice tariffe armonizzato
2941.90
TSCA
No
RTECS
AU355000

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