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518-47-8 - Fluorescein disodium salt - Acid Yellow 73 - C.I. 45350 - J61549 - Alfa Aesar

J61549 Fluorescein disodium salt

Codice CAS
518-47-8
Sinonimi
Acid Yellow 73
C.I. 45350

Dimensioni Prezzo ($) Quantità Disponibilità
100g 22,40
500g 59,20
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Fluorescein disodium salt

MDL
MFCD00167039
EINECS
208-253-0

Proprietà chimiche

Formula
C20H10Na2O5
Peso formula
376.28
Modulo
Powder
Solubilità
Soluble in water at 1mg/ml

Applicazioni

Fluorescein disodium salt is used as fluorescent tracer, has been utilized in studies as a drug model, as a penetrating dye . Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius.1 Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes.5 Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP). Additional reported uses include microscopy, as a gain medium in dye laser use and to detect latent blood stains in vitro. Common derivatives of Fluorescein include fluorescein isothiocyanate (FITC), eosin and Rose Bengal (sc-296278) and Rose Bengal sodium salt

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents. May be sensitive to prolonged exposure to light and to heat. Hygroscopic. Incompatible with strong oxidizers. Also incompatible with acids, acid salts and salts of heavy metals .

Letteratura

IR Politzer.; KT Crago.; T Hampton.; J Joseph. Effect of β-cyclodextrin on the fluorescence, absorption and lasing of rhodamine 6G, rhodamine B and fluorescein disodium salt in aqueous solutions. Chemical Physics Letters. 1989, 159, ( 2-3), 258-262.

JR Rubbmark.; SA Borgstrom. Absorption spectroscopy of laser-excited barium. Journal of Physics B. 1977, 10, ( 3), 258-262.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni precauzionali: P260-P201-P280-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,4159
Beilstein
3833041
Codice tariffe armonizzato
3204.12
TSCA
Yes
RTECS
LM5425000

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