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Dicloxacillin sodium salt is used in the treatment of staphylococci resistant to penicillin G. Dicloxacillin binds to specific penicillin-binding proteins in the bacterial cell wall and therefore inhibits the last stage of bacterial cell wall synthesis. Cell lysis, mediated by bacterial cell wall autolytic enzymes, is the result. Dicloxacillin may interfere with autolysin inhibitors.
Lambert K Sorensen.; Birthe M Rasmussen.; Joe O Boison.; Lily Keng. Simultaneous determination of six penicillins in cows' raw milk by a multiresidue high-performance liquid chromatographic method. Journal of Chromatography B: Biomedical Sciences and Applications. 1997, 694, (2), 383-391.
Lambert K. Sorensen.; Lena K. Snor.; Tina Elkaer.; Helga Hansen. Simultaneous determination of seven penicillins in muscle, liver and kidney tissues from cattle and pigs by a multiresidue high-performance liquid chromatographic method. Journal of Chromatography B: Biomedical Sciences and Applications. 1999, 734, (2), 307-318.
Dichiarazioni di rischio (UE): H303-H315-H319-H334-H317-H335
May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. May cause respiratory irritation.
Dichiarazioni precauzionali: P284-P261-P280a-P305+P351+P338-P405-P501a
Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.