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70-18-8 - L-Glutathione, reduced, 98+% - gamma-L-Glutamyl-L-cysteinylglycine - GSH - J62166 - Alfa Aesar

J62166 L-Glutathione, reduced, 98+%

Codice CAS
70-18-8
Sinonimi
gamma-L-Glutamyl-L-cysteinylglycine
GSH

Dimensioni Prezzo ($) Quantità Disponibilità
5g 41,90
25g 115,00
100g 388,00
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L-Glutathione, reduced, 98+%

MDL
MFCD00065939
EINECS
200-725-4

Proprietà chimiche

Formula
C10H17N3O6S
Peso formula
307.33
Modulo
Crystalline powder
Punto di fusione
ca 193° dec.
Solubilità
Soluble in water, dimethyl formamide, ethanol, phosphate buffered saline, diluted alcohol, liquid ammonia and dimethyl sulfoxide.

Applicazioni

A tripeptide used for the reductive cleavage of disulfide bonds L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions. It is also used in white wine production.

Note

Store in cool place. Incompatible with strong oxidizing agents.

Letteratura

Deheshi, S.; Dabiri, B.; Fan, S.; Tsang, M.; Rintoul, G. L. Changes in mitochondrial morphology induced by calcium or rotenone in primary astrocytes occur predominantly through ros-mediated remodeling. J. Neurochem. 2015, 133 (5), 684-699.

Li, X.; Zheng, L.; Wang, Y.; Zhang, N.; Lou, Y.; Xiao, T.; Liu, J. A novel electrocatalyst with high sensitivity in detecting glutathione reduced by 2-hydroxypropyl- β-cyclodextrin enveloped 10-methylphenothiazine. RSC Adv. 2015, 5 (88), 71749-71755.

Altri riferimenti

Merck
14,4475
Beilstein
1729812
Codice tariffe armonizzato
2930.90
TSCA
Yes
RTECS
MC0556000

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