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79645-27-5 - Tobramycin sulfate - J62995 - Alfa Aesar

J62995 Tobramycin sulfate

Codice CAS
79645-27-5
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
100mg 34,80
1g 294,58
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Tobramycin sulfate

MDL
MFCD00133864

Proprietà chimiche

Formula
(C18H37N5O9)2•5H2SO4
Peso formula
1425.41
Modulo
Powder
Solubilità
Soluble in water (50 mg/ml).

Applicazioni

Tobramycin sulfate is used as an antibiotic which is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. It is used to inhibit bacterial protein synthesis at the level of 30S (16S rRNA) and 70S ribosomal complex assembly. It is used to treat pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis and other soft-tissue infections. It is a potential therapy for sinus infections1. Product T1783 has been used to study antibiotic resistance2.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Letteratura

Alhariri M & Omri A. Efficacy of liposomal bismuth-ethanedithiol-loaded tobramycin after intratracheal administration in rats with pulmonary Pseudomonas aeruginosa infection. Antimicrob Agents Chemother.2013, 57, (1), 569-78.

Li M & Byron PR Tobramycin disposition in the rat lung following airway administration. J Pharmacol Exp Ther.2013, 347, (2), 318-24.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,9490
Codice tariffe armonizzato
2941.90
TSCA
No
RTECS
WK2110000

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