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15686-71-2 - Cephalexin hydrate, 97+% - J63172 - Alfa Aesar

J63172 Cephalexin hydrate, 97+%

Codice CAS
15686-71-2
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
5g 57,90
25g 217,00
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Cephalexin hydrate, 97+%

MDL
MFCD00167148
EINECS
239-773-6

Proprietà chimiche

Formula
C16H17N3O4S•xH2O
Peso formula
347.39(anhy)
Modulo
Powder
Solubilità
Soluble in DMSO and Methanol.

Applicazioni

Cephalexin is a cephalosporin antibiotic used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis. Cephalexin disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cephalexin antibiotics mimic the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Letteratura

Tomoko Sugiura et. al. PDZK1 regulates two intestinal solute carriers (Slc15a1 and Slc22a5) in mice. Drug Metabolism and Disposition. 200836 (6), 1181-1188.

Karolina Langowska et. al. Polymer nanoreactors shown to produce and release antibiotics locally. Chemical Communications. 201349 (2), 128-130 .

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H334-H317

May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.

Dichiarazioni precauzionali: P284-P261-P280g-P342+P311a-P363-P501a

Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. If experiencing respiratory symptoms: Call a POISON CENTER/doctor. Wash contaminated clothing before reuse. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,1974
Beilstein
965503
Codice tariffe armonizzato
2941.90
TSCA
No
RTECS
XI0350000

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