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24169-02-6 - Econazole nitrate - Ecostatin - 1-[2-(4-Chlorophenylmethoxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate - J63173 - Alfa Aesar

J63173 Econazole nitrate

Codice CAS
24169-02-6
Sinonimi
Ecostatin
1-[2-(4-Chlorophenylmethoxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate

Dimensioni Prezzo ($) Quantità Disponibilità
5g 53,80
25g 220,00
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Econazole nitrate

MDL
MFCD00058160
EINECS
246-053-5

Proprietà chimiche

Formula
C18H15Cl3N2O•HNO3
Peso formula
444.70
Modulo
Powder
Punto di fusione
158-163°
Solubilità
Soluble at 0.4mg/ml in DMSO. Sparingly soluble in water.

Applicazioni

Econazole nitrate is an antifungal medication often used as a cream to treat skin infections like tinea, ringworm and athlete's foot, personal care, cosmetic and pharmaceutical applications. It is used for studies on processes such as platelet serotonin uptake, prostanoid biosynthesis, EDHF-mediated relaxation, and Ca2+ transport pathways in thymic lymphocytes.

Note

Keep container tightly closed. Store away from oxidizing agents. Store in cool, dry conditions in well sealed containers.

Letteratura

Poonam Verma.; Kamla Pathak. Nanosized ethanolic vesicles loaded with econazole nitrate for the treatment of deep fungal infections through topical gel formulation. Nanomedicine: Nanotechnology, Biology and Medicine. 2012, 8, (4), 489-496.

Vanna Sanna.; Giuseppe Caria.; Alberto Mariani. Effect of lipid nanoparticles containing fatty alcohols having different chain length on the ex vivo skin permeability of Econazole nitrate. Powder Technology. 2010, 201, (1), 32-36.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H315-H319

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Dichiarazioni precauzionali: P280-P264-P270-P305+P351+P338-P362-P301+P312-P321-P332+P313-P337+P313-P501a

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,3502
Codice tariffe armonizzato
2933.29
TSCA
No
RTECS
NI4450000

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