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64603-90-3 - Isoguvacine hydrochloride, 99% - 1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid hydrochloride - J63243 - Alfa Aesar

J63243 Isoguvacine hydrochloride, 99%

Codice CAS
64603-90-3
Sinonimi
1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid hydrochloride

Dimensioni Prezzo ($) Quantità Disponibilità
100mg 358,44
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Isoguvacine hydrochloride, 99%

MDL
MFCD00055192

Proprietà chimiche

Formula
C6H9NO2•HCl
Peso formula
163.60
Modulo
Powder
Solubilità
Soluble in water

Applicazioni

Isoguvacine·HCl is an agonist of γ-amino butyric acid receptor. Isoguvacine interactions have many similar biochemical features of GABA synaptic function. Isoguvacine·HCl is a specific GABAA receptor agonist. This compound suppresses low magnesium induced seizure like events in organotypic hippocampal brain slices.

Note

Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Letteratura

Willian Seiji Korim.; Simon McMullan.; Sergio L. Cravo.; Paul M. Pilowsky. Asymmetrical changes in lumbar sympathetic nerve activity following stimulation of the sciatic nerve in rat. Brain Research. 2011, 1391, 60-70.

Takako Shimidzu.; Yoshinori Itoh.; Michiko Oka.; Tsuyoshi Ishima.; Yojiro Ukai.; Yoshiaki Yoshikuni.; Kiyoshi Kimura. Effect of a novel cognition enhancer NS-105 on learned helplessness in rats: Possible involvement of GABAB receptor up-regulation after repeated treatment. European Journal of Pharmacology. 1997, 338,(3), 225-232.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.39
TSCA
No
RTECS
US5908286

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