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59-33-6 - Pyrilamine maleate - Mepyramine maleate - N-(4-Methoxyphenyl)methyl-N',N'-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt - J63247 - Alfa Aesar

J63247 Pyrilamine maleate

Codice CAS
59-33-6
Sinonimi
Mepyramine maleate
N-(4-Methoxyphenyl)methyl-N',N'-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt

Dimensioni Prezzo ($) Quantità Disponibilità
25g 48,70
100g 166,00
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Pyrilamine maleate

MDL
MFCD00069333
EINECS
200-422-7

Proprietà chimiche

Formula
C17H23N3O.C4H4O4
Peso formula
401.46
Modulo
Powder
Solubilità
Soluble in water at 100mg/ml

Applicazioni

Pyrilamine maleate Selective inverse agonist for the H-1 histamine receptor. Pyrilamine Maleate is commonly utilized as a radioligand ([3H]Mepyramine) binding assay for the H1 receptor. And also used to exhibit blocking ability of KCNQ/M channels which is potentially related to an adverse effect seen in excess intake of antihistamines.

Note

Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Letteratura

Lijinsky, W. Chronic toxicity tests of pyrilamine maleate and methapyrilene hydrochloride in F344 rats.Food and Chemical Toxicology.1984, 22, (1), 27-30.

Jang O. Oh.; Charles A. Evans. Suppressive effects of pyrilamine maleate and d-lysergic acid diethylamide (LSD-25) on early corneal lesions produced in vitro by Newcastle disease virus (NDV) and compound 4880 ?.Virology.1960, 10, (1), 127-143.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P260-P201-P280g-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,7984
Codice tariffe armonizzato
2933.39
TSCA
Yes
RTECS
UT1225000

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