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Forskolin acts as an adenylyl cyclase activator. It is used in the treatment of hypertension, asthma, eczema, psoriasis, congestive heart failure, angina, stomachache, gastric and intestinal spasm. It also plays an important role in the treatment of rheumatism, heart, blood and circulation conditions and cancers. It is used to induce menstruation and as an oral contraceptive.
Wang, C.; Ruan, T.; Liu, J.; He, B.; Zhou, Q.; Jiang, G. Perfluorooctyl Iodide Stimulates Steroidogenesis in H295R Cells via a Cyclic Adenosine Monophosphate Signaling Pathway. Chem. Res. Toxicol. 2015, 28 (5), 848-854.
Roberts, S. C.; Bianco, A. C.; Stapleton, H. M. Disruption of Type 2 Iodothyronine Deiodinase Activity in Cultured Human Glial Cells by Polybrominated Diphenyl Ethers. Chem. Res. Toxicol. 2015, 28 (6), 1265-1274.
Dichiarazioni di rischio (UE): H303-H315-H319-H335
May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.