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9002-04-4 - Thrombin, bovine plasma - Factor IIa - EC 3.4.21.5 - J63383 - Alfa Aesar

J63383 Thrombin, bovine plasma

Codice CAS
9002-04-4
Sinonimi
Factor IIa
EC 3.4.21.5

Dimensioni Prezzo ($) Quantità Disponibilità
100kilounits 505,00
500kilounits 1427,00
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Thrombin, bovine plasma

MDL
MFCD00166053
EINECS
232-648-7

Proprietà chimiche

Modulo
Powder
Solubilità
Reconstitute in 0.9% sodium chloride

Applicazioni

Thrombin is a trypsin-like serine protease involved in a multitude of processes in the human body. Thrombin generation is the result of limited proteolysis of the vitamin K-dependent zymogen prothrombin. Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to fibrin which forms the fibrin gel of a haemostatic plug or a pathologic thrombus

Note

Lyophilized from a solution containing glycine, sodium chloride and calcium chloride. Specific activity is in the range of 90-250 NIH units/mg protein

Letteratura

Walter Kisiel.; William M. Canfield.; Lowell H. Ericsson.; Earl W. Davie. Anticoagulant properties of bovine plasma protein C following activation by thrombin.Biochemistry.1977, 16, (26), 5824-5831.

Walter Kisiel. Human plasma protein c: isolation, characterization, and mechanism of activation by α-thrombin.J Clin Invest.1979, 64, (3), 761-769..

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H334-H315-H319-H335

May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P285-P261-P280-P305+P351+P338-P304+P340-P342+P311-P362-P312-P405-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,9383
Codice tariffe armonizzato
3507.90
TSCA
Yes
RTECS
XO8950000

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