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1177-87-3 - Dexamethasone acetate - J63691 - Alfa Aesar

J63691 Dexamethasone acetate

Codice CAS
1177-87-3
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
250mg 52,50
1g 172,00
5g 636,00
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Dexamethasone acetate

MDL
MFCD00027407
EINECS
214-646-8

Proprietà chimiche

Formula
C24H31FO6
Peso formula
434.50
Modulo
Powder
Punto di fusione
240°
Solubilità
Soluble at 100 mg/ml in acetone

Applicazioni

Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It is also used for replacement therapy in adrenal insufficiency and in a screening test for the diagnosis of cushing's syndrome. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Letteratura

Leibowitz HM,; Kupferman A,; Stewart RH,; Kimbrough RL.Evaluation of dexamethasone acetate as a topical ophthalmic formulation. . Am J Ophthalmol. . 1978, 86 (3), 418-23..

Roberts CP,; Murphy AA,; Santanam N,; Parthasarathy S. The effect of RU 486 and related compounds on cultured macrophage differentiation and function. Am J Obstet Gynecol.. 1996, 175 (2), 248-57.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H317

May cause an allergic skin reaction.

Dichiarazioni precauzionali: P261-P280-P272-P363-P321-P333+P313-P302+P352-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Contaminated work clothing should not be allowed out of the workplace. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. IF ON SKIN: Wash with plenty of soap and water. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,2943
Beilstein
2342608
Codice tariffe armonizzato
2937.22
TSCA
Yes
RTECS
TU4050000

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