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7421-40-1 - Carbenoxolone disodium salt, 97+% - J63714 - Alfa Aesar

J63714 Carbenoxolone disodium salt, 97+%

Codice CAS
7421-40-1
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
1g 34,40
5g 136,00
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Carbenoxolone disodium salt, 97+%

MDL
MFCD00079043
EINECS
231-044-0

Proprietà chimiche

Formula
C34H48Na2O7
Peso formula
614.70
Modulo
Solid
Solubilità
Soluble in water to 100 mM.

Applicazioni

Carbenoxolone is anti-inflammatory. It is often used as a gap junction inhibitor in neuroscience research. Carbenoxolone is also an inhibitor of the steroid dehydrogenase enzymes 11 β-hydroxysteroid dehydrogenase (human) and 3α, 20 β-hydroxysteroid dehydrogenase (bacterial). It is used for the treatment of digestive tract ulcers, especially in the stomach. Used in the treatment of peptic, mainly gastric, ulcers. It is often used as a gap junction inhibitor in neuroscience research.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from heat.

Letteratura

L. Horwich,; R. Galloway.Treatment of gastric ulceration with carbenoxolone sodium: clinical and radiological evaluation.. Br Med J. . 1965 , 2 (5473), 1274-1277..

W. Hausmann,; A. L. Tarnoky. Biochemical Effects Of Short-Term Treatment With Carbenoxolone Disodium. British Journal of Pharmacology and Chemotherapy. 1966, 26 (2) , 412-420.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H303-H315-H319-H335

May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,1793
Codice tariffe armonizzato
2918.99
TSCA
No
RTECS
RK0250000

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