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9035-81-8 - Trypsin inhibitor, chicken egg whites - Trypsin inhibitor, ovomucoid - J63927 - Alfa Aesar

J63927 Trypsin inhibitor, chicken egg whites

Codice CAS
9035-81-8
Sinonimi
Trypsin inhibitor, ovomucoid

Dimensioni Prezzo ($) Quantità Disponibilità
500mg 60,75
1g 109,35
2g 206,55
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Trypsin inhibitor, chicken egg whites

MDL
MFCD00082102
EINECS
232-906-9

Proprietà chimiche

Modulo
Powder
Solubilità
Soluble in water (10 mg/ml), phosphate buffers (10 mg/ml), and balanced salt solutions (1 mg/ml).

Applicazioni

Soybean trypsin inhibior (STI) is a protein which reduces trypsin (a proteolytic enzyme) as well as plasma kallikrein, factor Xa and plasmin activity. Soybean trypsin inhibitor has demonstrated inhibition of human neutrophil elastase at an IC50=0.3 nM. At this concentration soybean trypsin inhibitor showed neither cytotoxic nor haemolytic effects on populations of human blood cells. In fibrin matrix, and without toxic effects, STI had a strong inhibitory effect on human umbilical vein endothelial cells migration and tubulogenesis.

Note

One mg inhibits at least 1.2 mg of trypsin with activity of at least 180 units/mg, when a unit is defined as the amount of protein that hydrolyzes 1micromole of TAME per mite at 25°C, pH 8.2 in the presence of 0.1M calcium.

Letteratura

Robert Huber.; Dietmar Kukla.; Wolfram Bode.; Peter Schwager.; Klaus Bartels.; Johann Deisenhofe.; Wolfgang Steigemann. Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor : II. Crystallographic refinement at 1.9 Å resolution.J. Mol. Biol. 1974, 89 (1),73-101 .

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H334-H317

May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.

Dichiarazioni precauzionali: P285-P261-P280-P342+P311-P363-P304+P341-P321-P333+P313-P302+P352-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. IF ON SKIN: Wash with plenty of soap and water. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
3504.00
TSCA
No

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