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2-Mercaptoethane sulfonic acid sodium salt is used as an adjuvant in cancer chemotherapy involving cyclophosphamide and ifosfamide. It is used as an antioxidant and cytoprotective agent in a wide variety of applications from protection from toxicity of therapeutic agents, such as cyclophosphamide to prevention from brain injury damage.
Ariela Marshall; Cindy McGrath; Drew Torigian; Nicholas Papanicolaou; Priti Lal; Carol Kaplan Tweed. Low-dose cyclophosphamide associated with hemorrhagic cystitis in a breast cancer patient. Breast Journal. 2012, 18,(3), 272-275.
Nicole J.Look Hong; Francis J.Hornicek; David C.Harmon; Edwin Choy; Yen-Lin Chen; Sam S.Yoon; G.Petur Nielsen; Jackie Szymonifka; Beow Y.Yeap; Thomas F.DeLaney; John T.Mullen. Neoadjuvant chemoradiotherapy for patients with high-risk extremity and truncal sarcomas: A 10-year single institution retrospective study. European Journal of Cancer. 2013, 49,(4), 875-883.
Dichiarazioni di rischio (UE): H303-H315-H319-H335
May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.